This issue of Cardiology Clinics, curated by Dr. Melinda Davis and Dr. Kathryn Lindley, will explore topics related to Pregnancy and Heart Disease. This issue is one of four selected each year by the series editorial board: Jamil A. Aboulhosn, David M. Shavelle, Terrence D. Welch, and Audrey H. Wu. Topics in this volume include, but are not limited to, Cardiovascular Contribution to Maternal Mortality, Risk stratification and The Pregnancy Heart Team, Cardiovascular Testing in Pregnant Women, Obstetric Considerations and Delivery Planning, Adult Congenital Heart Disease, Aortopathies and Vascular Disease, Arrhythmias, Hypertensive Disorders of Pregnancy, Ischemic Heart Disease, Pulmonary Arterial Hypertension, Peripartum Cardiomyopathy¸ Hypertrophic Cardiomyopathy, Valvular Heart Disease, Medication Safety during Pregnancy, and Delivering Coordinated Care from Preconception through Postpartum.