This second edition of a successful title bridging toxicology and environmental chemistry adopts a unique approach that 'follows' chemicals on a molecular level, from the environment through the different uptake mechanisms into the body. Along the way, this textbook explains the different routes of degradation and metabolism of the different classes of chemicals, linking general chemical properties to their toxicological equivalents. All the chapters have been thoroughly updated and the contents significantly expanded, including new chapters on modern pesticides, food chemicals and solvents, as well as a chapter discussing the difficulties of accurate measurements of carcinogenesis in man.The text is aimed at a wide audience ranging from pharmacologists to environmental chemists and toxicologists.